diff --git a/projects/rocprofiler-compute/CHANGELOG.md b/projects/rocprofiler-compute/CHANGELOG.md
index 459288e14c..bb1a80a58f 100644
--- a/projects/rocprofiler-compute/CHANGELOG.md
+++ b/projects/rocprofiler-compute/CHANGELOG.md
@@ -66,6 +66,8 @@ Full documentation for ROCm Compute Profiler is available at [https://rocm.docs.
 
 ### Changed
 
+* Change the default rocprof version to rocprofv3, this is used when environment variable "ROCPROF" is not set
+* Change the rocprof version for unit tests to rocprofv3 on all SoCs except MI100
 * Change normal_unit default to per_kernel
 * Change dependency from rocm-smi to amd-smi
 * Decrease profiling time by not collecting counters not used in post analysis
@@ -83,6 +85,7 @@ Full documentation for ROCm Compute Profiler is available at [https://rocm.docs.
 
 ### Known issues
 
+* Profiling on MI 100 will not work unless ROCPROF=rocprofv1 environment variable is explictly provided
 * GPU id filtering is not supported when using rocprof v3
 
 * Analysis of previously collected workload data will not work due to sysinfo.csv schema change
diff --git a/projects/rocprofiler-compute/docs/reference/compatible-accelerators.rst b/projects/rocprofiler-compute/docs/reference/compatible-accelerators.rst
index 65a3f70a1b..3dd2548f97 100644
--- a/projects/rocprofiler-compute/docs/reference/compatible-accelerators.rst
+++ b/projects/rocprofiler-compute/docs/reference/compatible-accelerators.rst
@@ -23,6 +23,9 @@ GPU specifications.
    * - Platform
      - Status
 
+   * - AMD Instinct™ MI350
+     - Supported ✅
+
    * - AMD Instinct™ MI300
      - Supported ✅
 
diff --git a/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx906.py b/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx906.py
deleted file mode 100644
index d0c34a1c9f..0000000000
--- a/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx906.py
+++ /dev/null
@@ -1,63 +0,0 @@
-##############################################################################bl
-# MIT License
-#
-# Copyright (c) 2021 - 2025 Advanced Micro Devices, Inc. All Rights Reserved.
-#
-# Permission is hereby granted, free of charge, to any person obtaining a copy
-# of this software and associated documentation files (the "Software"), to deal
-# in the Software without restriction, including without limitation the rights
-# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
-# copies of the Software, and to permit persons to whom the Software is
-# furnished to do so, subject to the following conditions:
-#
-# The above copyright notice and this permission notice shall be included in all
-# copies or substantial portions of the Software.
-#
-# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
-# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
-# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
-# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
-# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
-# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
-# SOFTWARE.
-##############################################################################el
-
-from rocprof_compute_soc.soc_base import OmniSoC_Base
-from utils.logger import console_error, demarcate
-from utils.mi_gpu_spec import mi_gpu_specs
-
-
-class gfx906_soc(OmniSoC_Base):
-    def __init__(self, args, mspec):
-        super().__init__(args, mspec)
-        self.set_arch("gfx906")
-        self.set_compatible_profilers(["rocprofv1"])
-        # Per IP block max number of simultaneous counters. GFX IP Blocks
-        self.set_perfmon_config({mi_gpu_specs.get_perfmon_config("gfx906")})
-
-        # Set arch specific specs
-        self._mspec._l2_banks = 16
-        self._mspec.lds_banks_per_cu = 32
-        self._mspec.pipes_per_gpu = 4
-
-    # -----------------------
-    # Required child methods
-    # -----------------------
-    @demarcate
-    def profiling_setup(self):
-        """Perform any SoC-specific setup prior to profiling."""
-        super().profiling_setup()
-        if self.get_args().roof_only:
-            console_error("%s does not support roofline analysis" % self.get_arch())
-        # Perfmon filtering
-        self.perfmon_filter(self.get_args().roof_only)
-
-    @demarcate
-    def post_profiling(self):
-        """Perform any SoC-specific post profiling activities."""
-        super().post_profiling()
-
-    @demarcate
-    def analysis_setup(self):
-        """Perform any SoC-specific setup prior to analysis."""
-        super().analysis_setup()
diff --git a/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx908.py b/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx908.py
index 0cc6f0fdeb..b4cdfe42f4 100644
--- a/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx908.py
+++ b/projects/rocprofiler-compute/src/rocprof_compute_soc/soc_gfx908.py
@@ -35,7 +35,7 @@ class gfx908_soc(OmniSoC_Base):
         super().__init__(args, mspec)
         self.set_arch("gfx908")
         self.set_compatible_profilers(
-            ["rocprofv1", "rocprofv3", "rocprofiler-sdk"]
+            ["rocprofv1"]
         )
         # Per IP block max number of simultaneous counters. GFX IP Blocks
         self.set_perfmon_config(mi_gpu_specs.get_perfmon_config("gfx908"))
diff --git a/projects/rocprofiler-compute/src/utils/utils.py b/projects/rocprofiler-compute/src/utils/utils.py
index 0a428432a2..43a12ae10b 100644
--- a/projects/rocprofiler-compute/src/utils/utils.py
+++ b/projects/rocprofiler-compute/src/utils/utils.py
@@ -323,7 +323,7 @@ def detect_rocprof(args):
     # detect rocprof
     if not "ROCPROF" in os.environ.keys():
         # default rocprof
-        rocprof_cmd = "rocprof"
+        rocprof_cmd = "rocprofv3"
     else:
         rocprof_cmd = os.environ["ROCPROF"]