diff --git a/projects/clr/hipamd/hip-config-amd.cmake b/projects/clr/hipamd/hip-config-amd.cmake
index 81f0aff5cd..4019e1846d 100755
--- a/projects/clr/hipamd/hip-config-amd.cmake
+++ b/projects/clr/hipamd/hip-config-amd.cmake
@@ -86,8 +86,10 @@ if(NOT AMDGPU_TARGETS)
     message(AUTHOR_WARNING "amdgpu-arch failed with error ${AMDGPU_ARCH_ERROR}")
     message("and the output is ${AMDGPU_ARCH_OUTPUT}")
   else()
-    string(REPLACE "\n" ";" AMDGPU_ARCH_OUTPUT ${AMDGPU_ARCH_OUTPUT})
-    set(AMDGPU_TARGETS ${AMDGPU_ARCH_OUTPUT} CACHE STRING "AMD GPU targets to compile for")
+    if (NOT AMDGPU_ARCH_OUTPUT STREQUAL "")
+      string(REPLACE "\n" ";" AMDGPU_ARCH_OUTPUT ${AMDGPU_ARCH_OUTPUT})
+      set(AMDGPU_TARGETS ${AMDGPU_ARCH_OUTPUT} CACHE STRING "AMD GPU targets to compile for")
+    endif()
   endif()
 endif()